BDBM50215433 2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-2-oxo-1,2-dihydropyrazin-1-yl]-N-[(4-carbamimidoyl-2-fluorophenyl)methyl]acetamide::CHEMBL390663

SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NC3CCC3)c2=O)-c2cccc(N)c2)c(F)c1

InChI Key InChIKey=OFFWLPCVTAWCJD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215433   

TargetCoagulation factor VII(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215433(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215433(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215433(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed