BDBM50215436 2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-2-oxo-1,2-dihydropyrazin-1-yl]-N-{[4-carbamimidoyl-2-(trifluoromethyl)phenyl]methyl}acetamide::CHEMBL230032

SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NC3CCC3)c2=O)-c2cccc(N)c2)c(c1)C(F)(F)F

InChI Key InChIKey=RXJICFAZSFAWGS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215436   

TargetCoagulation factor X(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215436(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215436(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215436(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50:  790nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed