BDBM50215699 CHEMBL400747::sodium (3R,5R)-7-(3,4-bis(4-fluorophenyl)-5-((3-hydroxyphenyl)carbamoyl)-1-isopropyl-1H-pyrrol-2-yl)-3,5-dihydroxyheptanoate

SMILES CC(C)n1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(c1C(=O)Nc1cccc(O)c1)-c1ccc(F)cc1)-c1ccc(F)cc1

InChI Key InChIKey=VWMVAZUDZKNVMN-KAYWLYCHSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215699   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215699(CHEMBL400747 | sodium (3R,5R)-7-(3,4-bis(4-fluorop...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed