BDBM50215701 CHEMBL250088::sodium (3R,5R)-7-(3,4-bis(4-fluorophenyl)-1-isopropyl-5-((3-methoxyphenyl)carbamoyl)-1H-pyrrol-2-yl)-3,5-dihydroxyheptanoate

SMILES COc1cccc(NC(=O)c2c(c(c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n2C(C)C)-c2ccc(F)cc2)-c2ccc(F)cc2)c1

InChI Key InChIKey=NPPXIWPMCDIBCA-KAYWLYCHSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215701   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215701(CHEMBL250088 | sodium (3R,5R)-7-(3,4-bis(4-fluorop...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed