BDBM50215793 4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carbamoyl)thiophen-3-ylamino)methyl)-N-methylpicolinamide::CHEMBL247618

SMILES CNC(=O)c1cc(CNc2ccsc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)ccn1

InChI Key InChIKey=CXDOYTGMCAHUID-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215793   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215793(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215793(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  61nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed