BDBM50216048 2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1-isoindolinone::2-[4-(4-Phenylpiperazin-1-yl)butyl]isoindolin-1-one::CHEMBL240774
SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)Cc2ccccc12
InChI Key InChIKey=SEAGRPUHJMFFQR-UHFFFAOYSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50216048
Affinity DataKi: 35.8nMAssay Description:Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...More data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Displacement of [3H]SCH 23390 from human Dopamine D5 receptor expressed in HEK293More data for this Ligand-Target Pair
Affinity DataKi: 189nMAssay Description:Displacement of [3H]Spiperone from human Dopamine receptor D2 isoform long expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataKi: 360nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid
Curated by ChEMBL
Universidad Complutense De Madrid
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human Dopamine D5 receptor in HEK293 cells assessed as change in SKF 38393-induced intracellular calcium responseMore data for this Ligand-Target Pair