BDBM50216176 CHEMBL230250::N-[(1S)-2-amino-1-benzylethyl]-2-{trans-[(2-methylcyclopropyl)methyl]amino}-6-[methyl(methylsulfonyl)amino]isonicotinamide
SMILES CC1CC1CNc1cc(cc(n1)N(C)S(C)(=O)=O)C(=O)N[C@H](CN)Cc1cc(F)cc(F)c1
InChI Key InChIKey=SGGMSEUTLOBCFL-ZVYVSMAVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50216176
Affinity DataIC50: 280nMAssay Description:Inhibition of BACE1 assessed as effect on soluble APPbeta N-terminal fragment secretion in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair