BDBM50216178 CHEMBL394850::N-[(1S)-1-benzyl-2-hydroxyethyl]-2-[(cyclopropylmethyl)(propyl)amino]-6-[(isopropylsulfonyl)(methyl)amino]isonicotinamide
SMILES CCCN(CC1CC1)c1cc(cc(n1)N(C)S(=O)(=O)C(C)C)C(=O)N[C@H](CO)Cc1cc(F)cc(F)c1
InChI Key InChIKey=IKGRUPPYIQOVJN-QHCPKHFHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50216178
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of BACE1 assessed as effect on soluble APPbeta N-terminal fragment secretion in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair