BDBM50216683 1-(5-iodonaphthalen-1-ylsulfonyl)-1,4-diazepane::CHEMBL249089

SMILES Ic1cccc2c(cccc12)S(=O)(=O)N1CCCNCC1

InChI Key InChIKey=GEHJIACZUFWBTK-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50216683   

TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50216683(1-(5-iodonaphthalen-1-ylsulfonyl)-1,4-diazepane | ...)
Affinity DataKi:  300nMAssay Description:Inhibition of MLCK by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMO15-related protein kinase Pfmrk(Plasmodium falciparum)
Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50216683(1-(5-iodonaphthalen-1-ylsulfonyl)-1,4-diazepane | ...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of Plasmodium falciparum PfmrkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50216683(1-(5-iodonaphthalen-1-ylsulfonyl)-1,4-diazepane | ...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of ROCK1 assessed as ATP cunsumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed