BDBM50216790 (3R)-6-cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-1,2,4-oxadiazol-5-yl]-N-hydroxyhexanamide::CHEMBL226852

SMILES ONC(=O)C[C@@H](CCCC1CCCCC1)c1nc(no1)-c1c[nH]c(=O)[nH]c1=O

InChI Key InChIKey=SWOIHXOGQYPPNC-GFCCVEGCSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50216790   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216790((3R)-6-cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216790((3R)-6-cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216790((3R)-6-cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216790((3R)-6-cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human procollagen C-proteinase expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216790((3R)-6-cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50:  4.96E+4nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216790((3R)-6-cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50:  7.96E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed