BDBM50218174 (R)-2-(2-(4-(2-phenylthiazol-4-yl)phenoxy)ethylamino)-1-(pyridin-3-yl)ethanol::CHEMBL250144

SMILES O[C@@H](CNCCOc1ccc(cc1)-c1csc(n1)-c1ccccc1)c1cccnc1

InChI Key InChIKey=BJYIHFRHJDQJJX-QHCPKHFHSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50218174   

TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50218174((R)-2-(2-(4-(2-phenylthiazol-4-yl)phenoxy)ethylami...)
Affinity DataKi:  150nMAssay Description:Displacement of [125I]iodocyanopindolol from human adrenergic beta-1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50218174((R)-2-(2-(4-(2-phenylthiazol-4-yl)phenoxy)ethylami...)
Affinity DataKi:  500nMAssay Description:Displacement of [125I]iodocyanopindolol from human adrenergic beta-2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50218174((R)-2-(2-(4-(2-phenylthiazol-4-yl)phenoxy)ethylami...)
Affinity DataEC50:  580nMAssay Description:Agonist activity at human adrenergic beta-3 receptor expressed in CHO cells assessed as cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed