BDBM50218711 8-hydroxy-3-(3-methoxy-4-nitrophenyl)-5H-dibenzo[b,e][1,4]-diazepin-11(10H)-one::CHEMBL243491

SMILES COc1cc(ccc1N)-c1ccc2c(Nc3ccc(O)cc3NC2=O)c1

InChI Key InChIKey=CAJKSJQSVCOHBH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218711   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218711(8-hydroxy-3-(3-methoxy-4-nitrophenyl)-5H-dibenzo[b...)
Affinity DataEC50: >5.93E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218711(8-hydroxy-3-(3-methoxy-4-nitrophenyl)-5H-dibenzo[b...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed