BDBM50219114 CHEMBL244773::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-trans-but-2-enyl)-4-(3-methylpyridin-2-yl)benzamide::US8748608, 11
SMILES Cc1cccnc1-c1ccc(cc1)C(=O)NC\C=C\CN1CCN(CC1)c1cccc(Cl)c1Cl
InChI Key InChIKey=MTJYJBYKMIGLMS-NSCUHMNNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50219114
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataKi: 1.60nM IC50: 25.6nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataKi: 1.60nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Binding affinity to human 5HT2C receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 46.9nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 92nMAssay Description:Displacement of [125I]IABN from human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 92nMAssay Description:Binding affinity to human 5HT1A receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: 368nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in HEK293 cells by mitogenesis assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: 368nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
The United States of America As Represented By The Secretary of The Department of Health and Human Services
US Patent
Affinity DataIC50: 25.6nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in HEK293 cells by mitogenesis assayMore data for this Ligand-Target Pair