BDBM50219945 CHEMBL240273::N-((1r,4r)-4-(2-(4-(3-cyano-5-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)cyclohexyl)-2-oxo-1,2,3,4-tetrahydroquinoline-6-sulfonamide

SMILES N#Cc1cc(N2CCN(CC[C@H]3CC[C@H](NS(=O)(=O)c4ccc5c(c4)CCC(=O)N5)CC3)CC2)cc(C(F)(F)F)c1

InChI Key InChIKey=HVFQVLBUJHAZFN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219945   

TargetD(3) dopamine receptor(Rat)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219945BDBM50219945(N-((1r,4r)-4-(2-(4-(3-cyano-5-(trifluoromethyl)phe...)
Affinity DataIC50: 0.700nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219945BDBM50219945(N-((1r,4r)-4-(2-(4-(3-cyano-5-(trifluoromethyl)phe...)
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed