BDBM50220045 CHEMBL206666::[(20-{[dimethyl(prop-2-en-1-yl)azaniumyl]methyl}-3,13-diazapentacyclo[11.7.0.0^{3,11}.0^{4,9}.0^{14,19}]icosa-1(20),4,6,8,10,14(19),15,17-octaen-10-yl)methyl]dimethylprop-2-en-1-ylazanium dibromide

SMILES C[N+](C)(CC=C)Cc1c2Cn3c(Cn2c2ccccc12)c(C[N+](C)(C)CC=C)c1ccccc31

InChI Key InChIKey=ORKNVPSCDPJCEW-UHFFFAOYSA-N

Data  4 KI  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50220045   

TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50220045(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
Affinity DataKi:  550nMAssay Description:Displacement of (+/-)-[3H]epibatidine from muscle type nAChR of Torpedo californica in hepes bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50220045(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H]methyllycaconitine from alpha7 nAChR in tsA201 cells co-expressed with Ric3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50220045(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
Affinity DataKi:  3.98E+3nMAssay Description:Displacement of [3H]methyllycaconitine from human alpha-7 in tsA201 cells coexpressed with 5HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50220045(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]GR65630 from human 5HT3A receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50220045(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at human glycine alpha-1 receptor in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50220045(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
Affinity DataEC50:  2.29E+3nMAssay Description:Inhibition of [3H]NMS dissociation from muscarinic M2 receptor in hepes bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50220045(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
Affinity DataIC50:  3.00E+4nMAssay Description:Antagonist activity at human alpha-7 nAChR in tsA201 cells coexpressed with Ric3 by FMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50220045(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
Affinity DataEC50:  110nMAssay Description:Inhibition of [3H]NMS dissociation from muscarinic M2 receptor in Na,K,Pi bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50220045(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed