BDBM50220547 4,5-Dibromo-1H-pyrrole-2-carboxylic acid [3-(2-amino-1H-imidazol-4-yl)-allyl]-amide::4,5-Dibromo-1H-pyrrole-2-carboxylic acid [3-(2-amino-3H-imidazol-4-yl)-allyl]-amide::CHEMBL397591::oroidin::oroidin base
SMILES Nc1ncc(C=CCNC(=O)c2cc(Br)c(Br)[nH]2)[nH]1
InChI Key InChIKey=QKJAXHBFQSBDAR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50220547
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
University Of London
Curated by ChEMBL
University Of London
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Inhibition of Plasmodium falciparum FabI in presence of variable crotonyl-coA levelMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
University Of London
Curated by ChEMBL
University Of London
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Inhibition of Plasmodium falciparum FabI in presence of variable NADH levelsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 3(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:Inhibition of rat Kv1.3 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human N-terminal Ecto-5'-nucleotidaseMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human Kv1.3 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 4(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human Kv1.4 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 6(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat Kv1.6 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 6(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 1(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human Kv1.1 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 4(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of rat Kv1.4 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 2(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Kv1.2 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair