BDBM50220688 (R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(4,4-dimethylcyclohexyl)piperidin-1-yl)-3-(4-fluorophenyl)-1-oxopropan-2-yl)-4-methylpiperazine-2-carboxamide::CHEMBL249322

SMILES CN1CCN[C@H](C1)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(CC1)(C1CCC(C)(C)CC1)C(=O)NC(C)(C)C

InChI Key InChIKey=LNCCYFHBELRZJF-RRPNLBNLSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50220688   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50220688((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(4,4-dimet...)
Affinity DataIC50:  162nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50220688((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(4,4-dimet...)
Affinity DataEC50:  546nMAssay Description:Antagonist activity at human MC4R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50220688((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(4,4-dimet...)
Affinity DataEC50:  1.12E+3nMAssay Description:Antagonist activity at human MC5R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50220688((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(4,4-dimet...)
Affinity DataEC50:  241nMAssay Description:Antagonist activity at human MC3R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed