BDBM50220699 (R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(4-methylcyclohexyl)piperidin-1-yl)-3-(4-fluorophenyl)-1-oxopropan-2-yl)-4-methylpiperazine-2-carboxamide::CHEMBL249321

SMILES CC1CCC(CC1)C1(CCN(CC1)C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@H]1CN(C)CCN1)C(=O)NC(C)(C)C

InChI Key InChIKey=OHUUAUIQJKMPAV-RICNADKYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50220699   

TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50220699((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(4-methylc...)
Affinity DataEC50:  230nMAssay Description:Antagonist activity at human MC3R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50220699((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(4-methylc...)
Affinity DataIC50:  6.80nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50220699((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(4-methylc...)
Affinity DataEC50:  888nMAssay Description:Antagonist activity at human MC5R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50220699((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(4-methylc...)
Affinity DataEC50:  10nMAssay Description:Antagonist activity at human MC4R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed