BDBM50220780 CHEMBL299452

SMILES Fc1ccc(N2CCN(CCCn3c(=O)cc[nH]c3=O)CC2)c(OCC(F)(F)F)c1

InChI Key InChIKey=UZNAGRGAFAEPBA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50220780   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220780(CHEMBL299452)
Affinity DataKi:  1.30nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220780(CHEMBL299452)
Affinity DataKi:  32nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50220780(CHEMBL299452)
Affinity DataKi:  100nMAssay Description:Inhibition of [3H]prazosin binding to CHO-K1 whole cells expressing human cloned Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed