BDBM50220864 2-(3-(4-(4-fluorophenyl)-5,6-dihydropyridin-1(2H)-yl)propyl)quinazolin-4(3H)-one::2-{3-[4-(4-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-3H-quinazolin-4-one::CHEMBL251027

SMILES Fc1ccc(cc1)C1=CCN(CCCc2nc3ccccc3c(=O)[nH]2)CC1

InChI Key InChIKey=JFSNQOXGPKPECX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50220864   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220864(2-(3-(4-(4-fluorophenyl)-5,6-dihydropyridin-1(2H)-...)
Affinity DataIC50:  8.90nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220864(2-(3-(4-(4-fluorophenyl)-5,6-dihydropyridin-1(2H)-...)
Affinity DataIC50:  304nMAssay Description:Inhibition of PARP1 (unknown origin) after 15 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220864(2-(3-(4-(4-fluorophenyl)-5,6-dihydropyridin-1(2H)-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed