BDBM50221551 4-chloro-3-(5-methyl-3-(4-(piperazin-1-ylsulfonyl)phenylamino)benzo[e][1,2,4]triazin-7-yl)phenol::CHEMBL250623::US8481536, 512

SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)N3CCNCC3)nc12)-c1cc(O)ccc1Cl

InChI Key InChIKey=PDEWZRGITAXNMH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221551   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221551(4-chloro-3-(5-methyl-3-(4-(piperazin-1-ylsulfonyl)...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50221551(4-chloro-3-(5-methyl-3-(4-(piperazin-1-ylsulfonyl)...)
Affinity DataIC50:  6.60nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent