BDBM50221555 4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)propylsulfonyl)phenylamino)benzo[e][1,2,4]triazin-7-yl)phenol::CHEMBL399268::US8481536, 511::US8481536, 613

SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)CCCN3CCCC3)nc12)-c1cc(O)ccc1Cl

InChI Key InChIKey=RCZHVXSTTOXWRM-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50221555   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221555(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50221555(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)
Affinity DataIC50:  5nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50221555(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)
Affinity DataIC50:  2.90nMAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent