BDBM50221704 9-(3,4-dimethoxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione::CHEMBL392335

SMILES COc1ccc(CCN2CCCn3c2nc2n(C)c(=O)n(C)c(=O)c32)cc1OC

InChI Key InChIKey=NVPCMICHUTXKJC-UHFFFAOYSA-N

Data  1 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50221704   

TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50221704(9-(3,4-dimethoxyphenethyl)-1,3-dimethyl-6,7,8,9-te...)
Affinity DataKi:  1.21E+3nMAssay Description:Displacement of [3H]MSX2 from adenosine A2A receptor in rat brain striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 55(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50221704(9-(3,4-dimethoxyphenethyl)-1,3-dimethyl-6,7,8,9-te...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at Prolink1-tagged human GPR55 receptor expressed in CHO cells assessed as inhibition of lysophosphatidylinositol-induced beta ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 55(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50221704(9-(3,4-dimethoxyphenethyl)-1,3-dimethyl-6,7,8,9-te...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Prolink1-tagged human GPR55 receptor expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-arachidonyl glycine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50221704(9-(3,4-dimethoxyphenethyl)-1,3-dimethyl-6,7,8,9-te...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Prolink1-tagged human GPR18 receptor expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-arachidonyl glycine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50221704(9-(3,4-dimethoxyphenethyl)-1,3-dimethyl-6,7,8,9-te...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at Prolink1-tagged human GPR18 receptor expressed in CHO cells assessed as inhibition of THC-induced beta arrestin recruitment af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed