BDBM50222498 CHEMBL400512::N-(3,5-bis(trifluoromethyl)phenyl)-2-(pyridin-4-ylmethylamino)nicotinamide

SMILES FC(F)(F)c1cc(NC(=O)c2cccnc2NCc2ccncc2)cc(c1)C(F)(F)F

InChI Key InChIKey=GTODNZCUIOSWJB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222498   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50222498(CHEMBL400512 | N-(3,5-bis(trifluoromethyl)phenyl)-...)
Affinity DataKi:  8nMAssay Description:Inhibition of phosphorylated-Kdr after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed