BDBM50222821 2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(4-chloro-phenyl)-isonicotinamide::CHEMBL248835

SMILES Clc1ccc(NC(=O)c2ccnc(NC(=O)COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)c2)cc1

InChI Key InChIKey=KXAKUYHOMVNFBQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222821   

TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222821(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(4-...)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222821(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(4-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222821(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(4-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed