BDBM50224575 (S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-oxopyrazolidin-1-yl)ethyl)benzoic acid::CHEMBL249953

SMILES O[C@H](CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Br)c1

InChI Key InChIKey=MMKYRZFPISEJKE-HXUWFJFHSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50224575   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224575((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...)
Affinity DataKi:  13nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224575((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...)
Affinity DataKi:  3.07E+3nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224575((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50224575((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed