BDBM50227709 CHEMBL251917::N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl)-3-methylphenyl)piperidin-1-ylsulfonyl)-2-methylpropanamide

SMILES Cc1cc(ccc1-c1cccc(OCCO)n1)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO

InChI Key InChIKey=YVBOXQAMDNUBQA-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50227709   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50227709(CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...)
Affinity DataIC50:  2.42E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50227709(CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...)
Affinity DataIC50:  2.01E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50227709(CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...)
Affinity DataIC50:  2.42E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50227709(CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...)
Affinity DataIC50:  2.01E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50227709(CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227709(CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...)
Affinity DataIC50:  529nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50227709(CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50227709(CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227709(CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...)
Affinity DataIC50:  529nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50227709(CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed