BDBM50227754 (R)-3-(4-(3-(1-(5-chloro-3-methylbenzo[b]thiophene-2-carboxamido)ethyl)-5-fluorophenoxy)-2-ethylphenyl)propanoic acid::CHEMBL401236

SMILES CCc1cc(Oc2cc(F)cc(c2)[C@@H](C)NC(=O)c2sc3ccc(Cl)cc3c2C)ccc1CCC(O)=O

InChI Key InChIKey=WQCJKMGDGUHOFD-QGZVFWFLSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50227754   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227754((R)-3-(4-(3-(1-(5-chloro-3-methylbenzo[b]thiophene...)
Affinity DataIC50:  50nMAssay Description:Displacement of [3H]-2-methyl-2-(4-{3-{propyl-(5-pyridin-2-yl-thiophene-2-sulfonyl)-amino}-propyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227754((R)-3-(4-(3-(1-(5-chloro-3-methylbenzo[b]thiophene...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human PPARdelta expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227754((R)-3-(4-(3-(1-(5-chloro-3-methylbenzo[b]thiophene...)
Affinity DataEC50:  163nMAssay Description:Agonist activity at human PPARgamma expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227754((R)-3-(4-(3-(1-(5-chloro-3-methylbenzo[b]thiophene...)
Affinity DataIC50:  50nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227754((R)-3-(4-(3-(1-(5-chloro-3-methylbenzo[b]thiophene...)
Affinity DataIC50:  9.34E+3nMAssay Description:Displacement of [3H]-2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227754((R)-3-(4-(3-(1-(5-chloro-3-methylbenzo[b]thiophene...)
Affinity DataIC50:  9.33E+3nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227754((R)-3-(4-(3-(1-(5-chloro-3-methylbenzo[b]thiophene...)
Affinity DataIC50:  5nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227754((R)-3-(4-(3-(1-(5-chloro-3-methylbenzo[b]thiophene...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]-2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed