BDBM50228421 CHEMBL238493::diphenyl 1-(methylsulfonylamino)-2-(4-guanidinophenyl)-ethanephosphonate

SMILES [#6]S(=O)(=O)[#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1

InChI Key InChIKey=IBIDHFLEIDMKCW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50228421   

TargetProthrombin(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228421(CHEMBL238493 | diphenyl 1-(methylsulfonylamino)-2-...)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228421(CHEMBL238493 | diphenyl 1-(methylsulfonylamino)-2-...)
Affinity DataIC50:  2.50E+5nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228421(CHEMBL238493 | diphenyl 1-(methylsulfonylamino)-2-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228421(CHEMBL238493 | diphenyl 1-(methylsulfonylamino)-2-...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228421(CHEMBL238493 | diphenyl 1-(methylsulfonylamino)-2-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed