BDBM50228423 CHEMBL239536::ethyl 1-(diphenoxyphosphoryl)-2-(4-guanidinophenyl)ethylcarbamate

SMILES [#6]-[#6]-[#8]-[#6](=O)-[#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1

InChI Key InChIKey=PIFJHAXQZFBLCQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50228423   

TargetTissue-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228423(CHEMBL239536 | ethyl 1-(diphenoxyphosphoryl)-2-(4-...)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of human recombinant tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228423(CHEMBL239536 | ethyl 1-(diphenoxyphosphoryl)-2-(4-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228423(CHEMBL239536 | ethyl 1-(diphenoxyphosphoryl)-2-(4-...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228423(CHEMBL239536 | ethyl 1-(diphenoxyphosphoryl)-2-(4-...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed