BDBM50230100 4-fluoro-N-(5-(4-fluorobenzylthio)-1,3,4-thiadiazol-2-yl)benzamide::CHEMBL255738::N-(5-(4-fluorobenzylthio)-1,3,4-thiadiazol-2-yl)-4-fluorobenzamide

SMILES Fc1ccc(CSc2nnc(NC(=O)c3ccc(F)cc3)s2)cc1

InChI Key InChIKey=ZDYQINDXPNAOKX-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50230100   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Institute Of Molecular Genetics Igm-Cnr

Curated by ChEMBL
LigandPNGBDBM50230100(4-fluoro-N-(5-(4-fluorobenzylthio)-1,3,4-thiadiazo...)
Affinity DataKi:  100nMAssay Description:Inhibition of histidine-tagged human recombinant ABL expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Institute Of Molecular Genetics Igm-Cnr

Curated by ChEMBL
LigandPNGBDBM50230100(4-fluoro-N-(5-(4-fluorobenzylthio)-1,3,4-thiadiazo...)
Affinity DataKi:  120nMAssay Description:Inhibition of histidine-tagged human recombinant ABL expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Institute Of Molecular Genetics Igm-Cnr

Curated by ChEMBL
LigandPNGBDBM50230100(4-fluoro-N-(5-(4-fluorobenzylthio)-1,3,4-thiadiazo...)
Affinity DataKi:  470nMAssay Description:Mixed-type inhibition of histidine-tagged human recombinant ABL expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institute Of Molecular Genetics Igm-Cnr

Curated by ChEMBL
LigandPNGBDBM50230100(4-fluoro-N-(5-(4-fluorobenzylthio)-1,3,4-thiadiazo...)
Affinity DataKi:  550nMAssay Description:Inhibition of histidine-tagged human recombinant SRC expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institute Of Molecular Genetics Igm-Cnr

Curated by ChEMBL
LigandPNGBDBM50230100(4-fluoro-N-(5-(4-fluorobenzylthio)-1,3,4-thiadiazo...)
Affinity DataKi:  550nMAssay Description:Inhibition of histidine-tagged human recombinant SRC expressed in baculovirus system assessed as [gamma32P]ATP utilization after 10 mins by liquid sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed