BDBM50231449 CHEMBL398711::N-(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-2,3-dihydro-1H-inden-1-yl)-2,2,2-trifluoroacetamide
SMILES FC(F)(F)C(=O)NC1CCc2cc(CCN3CCN(CC3)c3nsc4ccccc34)ccc12
InChI Key InChIKey=NATFNVDYLPURMJ-UHFFFAOYSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50231449
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in Swiss 3T3 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]prazosin from rat adrenergic alpha1A receptor expressed in fibroblast cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]8OHDPAT from human 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]spiperone from human D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 143nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair