BDBM50232019 CHEMBL4088518
SMILES Cc1cc(Oc2cc(ncn2)N2CCOCC2)ccc1NC(=O)Nc1cc(on1)C(C)(C)C
InChI Key InChIKey=LWUDZNKHMLEZCF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50232019
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged ERK1 expressed in Escherichia coli in presence of [gamma33P]ATP by HTRF assayMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged RAF1 (306-end residues) expressed in baculovirus infected Sf21 cells in presence of [gamma33P]A...More data for this Ligand-Target Pair