BDBM50232021 CHEMBL4062521
SMILES CNc1cc(Oc2ccc(NC(=S)Nc3ccccc3)cc2F)ncn1
InChI Key InChIKey=JRGVJPCQXIRWRD-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50232021
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged RAF1 (306-end residues) expressed in baculovirus infected Sf21 cells in presence of [gamma33P]A...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged ERK1 expressed in Escherichia coli in presence of [gamma33P]ATP by HTRF assayMore data for this Ligand-Target Pair