BDBM50232022 CHEMBL4066428

SMILES CNc1cc(Oc2ccc(NC(=S)Nc3ccccc3)cc2C)ncn1

InChI Key InChIKey=JRCHCJQIOAYJIC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232022   

TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50232022(CHEMBL4066428)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged ERK1 expressed in Escherichia coli in presence of [gamma33P]ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50232022(CHEMBL4066428)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged RAF1 (306-end residues) expressed in baculovirus infected Sf21 cells in presence of [gamma33P]A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed