BDBM50232029 CHEMBL4105004

SMILES CNc1cc(Oc2ccc(NC(=O)Nc3ccc(cc3)C(F)(F)F)c(C)c2)ncn1

InChI Key InChIKey=RGRAHQLJPCEFAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232029   

TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50232029(CHEMBL4105004)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged ERK1 expressed in Escherichia coli in presence of [gamma33P]ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50232029(CHEMBL4105004)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged RAF1 (306-end residues) expressed in baculovirus infected Sf21 cells in presence of [gamma33P]A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed