BDBM50232031 CHEMBL4093023

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3cc(ncn3)N3CCCCC3)c(F)c2)no1

InChI Key InChIKey=OEZKNJOTRJGSHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232031   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50232031(CHEMBL4093023)
Affinity DataIC50:  89nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged RAF1 (306-end residues) expressed in baculovirus infected Sf21 cells in presence of [gamma33P]A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50232031(CHEMBL4093023)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged ERK1 expressed in Escherichia coli in presence of [gamma33P]ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed