BDBM50232152 (1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroethoxy)-2-methoxyphenyl)methanol::(3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol::CHEMBL402143

SMILES COc1c(OCCF)cccc1C(O)C1CCN(CCc2ccc(F)cc2)CC1

InChI Key InChIKey=QCFZUTYIUYQTPW-UHFFFAOYSA-N

Data  25 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50232152   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  9.02nMAssay Description:Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cells by liquid scintillation analyserMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  71nMAssay Description:Inhibition of human cloned 5-HT2C receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  116nMAssay Description:Inhibition of human cloned 5HT7 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  148nMAssay Description:Inhibition of human cloned alpha2C adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  299nMAssay Description:Inhibition of human cloned 5HT2B receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  325nMAssay Description:Inhibition of human cloned alpha1B adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  374nMAssay Description:Inhibition of human cloned histamine H1 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  544nMAssay Description:Inhibition of human cloned dopamine D4 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  706nMAssay Description:Inhibition of human cloned 5HT1D receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  899nMAssay Description:Inhibition of human cloned dopamine D1 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  1.85E+3nMAssay Description:Inhibition of human cloned 5HT1B receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  3.18E+3nMAssay Description:Inhibition of human cloned histamine H2 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  3.52E+3nMAssay Description:Inhibition of human cloned SERT by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi:  3.89E+3nMAssay Description:Inhibition of human cloned 5HT6 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT1A receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned mu opioid receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT1E receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned DAT by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned dopamine D2 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned beta3 adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned alpha2A adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT5A receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned histamine H3 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50232152((1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroe...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT3 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed