BDBM50232391 CHEMBL4100119

SMILES Cc1nn(c2NC(=O)CC(OCc3cc(F)cc4COCOc34)c12)-c1ncnc2nc[nH]c12

InChI Key InChIKey=GGHNDEIHCIKSNC-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50232391   

TargetG-protein coupled receptor 39(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50232391(CHEMBL4100119)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GPR39 expressed in HEK293 cells co-expressing Galphaq assessed as myo-[2-3H]inositol phosphate accumulation measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 39(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50232391(CHEMBL4100119)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human GPR39 expressed in HEK293 cells co-expressing Galphaq assessed as myo-[2-3H]inositol phosphate accumulation in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 39(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50232391(CHEMBL4100119)
Affinity DataEC50:  12nMAssay Description:Agonist activity at GPR39 (unknown origin) expressed in COS7 cells co-expressing Galphas assessed as increase in intracellular cAMP level in presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 39(Mus musculus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50232391(CHEMBL4100119)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at mouse GPR39 expressed in HEK293 cells co-expressing Galphaq assessed as myo-[2-3H]inositol phosphate accumulation in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed