BDBM50232779 CHEMBL4060711

SMILES COc1ccc2C(=O)\C(Oc2c1CN1CCNCC1)=C\c1c[nH]c2nc(C)ccc12

InChI Key InChIKey=NZTGSWDBRZMTBV-JAIQZWGSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232779   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50232779(CHEMBL4060711)
Affinity DataIC50:  0.640nMAssay Description:Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50232779(CHEMBL4060711)
Affinity DataIC50:  300nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PIM2 (1 to 311 residues) expressed in baculovirus infected sf21 cells using S6K2 pe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed