BDBM50232792 CHEMBL4074240

SMILES COc1ccc(cc1)-c1nc2ccccc2c(C(=O)N[C@@H](C)c2ccccc2)c1CN1CCC(CC1)N1CCCCC1

InChI Key InChIKey=JPSDEHLEZUNMAR-SANMLTNESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232792   

TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50232792(CHEMBL4074240)
Affinity DataIC50:  5.01E+3nMAssay Description:Antagonist activity at human TRPV4 expressed in HEK293 cells assessed as inhibition of GSK634775A-induced calcium influx preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50232792(CHEMBL4074240)
Affinity DataIC50:  320nMAssay Description:Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of GSK634775A-induced calcium influx preincubated for 10 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed