BDBM50232795 CHEMBL4092276

SMILES C[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=XAQPCKKFCKSQOW-SANMLTNESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50232795   

TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50232795(CHEMBL4092276)
Affinity DataIC50:  320nMAssay Description:Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of GSK634775A-induced calcium influx preincubated for 10 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50232795(CHEMBL4092276)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at human TRPV4 expressed in HEK293 cells assessed as inhibition of GSK634775A-induced calcium influx preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50232795(CHEMBL4092276)
Affinity DataIC50:  100nMAssay Description:Inhibition of NK2 receptor (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50232795(CHEMBL4092276)
Affinity DataIC50:  8nMAssay Description:Inhibition of NK3 receptor (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed