BDBM50233698 CHEMBL254498::N-(4-(2-cyanofuran-5-carboxamido)-3-(piperidin-1-yl)phenyl)-N,4-dimethylpiperazine-1-carboxamide

SMILES CN(C(=O)N1CCN(C)CC1)c1ccc(NC(=O)c2ccc(o2)C#N)c(c1)N1CCCCC1

InChI Key InChIKey=NRVCJJDVPMSERN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233698   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50233698(CHEMBL254498 | N-(4-(2-cyanofuran-5-carboxamido)-3...)
Affinity DataIC50:  83nMAssay Description:Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed