BDBM50233762 (R)-tert-butyl 1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)-3-(2-(trifluoromethoxy)phenyl)propan-2-ylcarbamate::CHEMBL253660

SMILES CC(C)(C)OC(=O)N[C@H](Cc1ccccc1OC(F)(F)F)C(=O)NCc1nc2cccnc2n1C1(CC1)c1ccccc1

InChI Key InChIKey=NVLCLKSNVBSVHX-HSZRJFAPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50233762   

TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50233762((R)-tert-butyl 1-oxo-1-((3-(1-phenylcyclopropyl)-3...)
Affinity DataIC50:  985nMAssay Description:Blockade of human Nav1.8 channel expressed in HEK293 cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50233762((R)-tert-butyl 1-oxo-1-((3-(1-phenylcyclopropyl)-3...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50233762((R)-tert-butyl 1-oxo-1-((3-(1-phenylcyclopropyl)-3...)
Affinity DataIC50:  148nMAssay Description:Blockade of human Nav1.7 channel expressed in HEK293 cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed