BDBM50233775 (R)-tert-butyl 3-(2-chloro-6-fluorophenyl)-1-oxo-1-((3-(1-phenylcyclopropyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)propan-2-ylcarbamate::CHEMBL400845

SMILES CC(C)(C)OC(=O)N[C@H](Cc1c(F)cccc1Cl)C(=O)NCc1nc2cccnc2n1C1(CC1)c1ccccc1

InChI Key InChIKey=BSKMBSPKWWECJR-XMMPIXPASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233775   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50233775((R)-tert-butyl 3-(2-chloro-6-fluorophenyl)-1-oxo-1...)
Affinity DataIC50:  147nMAssay Description:Blockade of human Nav1.7 channel expressed in HEK293 cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50233775((R)-tert-butyl 3-(2-chloro-6-fluorophenyl)-1-oxo-1...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed