BDBM50233891 CHEMBL4074167

SMILES Cc1csc2nc([nH]c(=O)c12)C(=O)NCc1cccc(CNC(=O)Cc2nc[nH]n2)c1

InChI Key InChIKey=JRBXTZBABOIXPG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50233891   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233891(CHEMBL4074167)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of APMA-activated recombinant human MMP-2 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233891(CHEMBL4074167)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233891(CHEMBL4074167)
Affinity DataIC50:  480nMAssay Description:Inhibition of APMA-activated recombinant human MMP-8 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233891(CHEMBL4074167)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed