BDBM50234829 CHEMBL4100760

SMILES COc1cc2O\C(=C/c3ccc(CN4CCCCC4)c(O)c3)C(=O)c2cc1OC

InChI Key InChIKey=GUEFWBGMYQHYFE-JJFYIABZSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234829   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50234829(CHEMBL4100760)
Affinity DataKi:  12nMAssay Description:Mixed-type inhibition of Electrophorus electricus AChE pretreated for 15 mins followed by varying levels of acetylthiocholine iodide substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50234829(CHEMBL4100760)
Affinity DataIC50:  37nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50234829(CHEMBL4100760)
Affinity DataIC50:  21nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50234829(CHEMBL4100760)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of AChE in rat brain cortex homogenates using acetylthiocholine iodide as substrate in presence of BuChE inhibitor tetraisopropyl pyrophos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed