BDBM50234948 CHEMBL4078429

SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OC(N)=O)[C@H](C)CCC(=O)N[C@H](CC(O)=O)Cc1c[nH]c2ccccc12

InChI Key InChIKey=FAAZTHVEPPRZQA-AIDMMIJQSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50234948   

TargetEphrin type-A receptor 2(Homo sapiens (Human))
University Of Parma

Curated by ChEMBL
LigandPNGBDBM50234948(CHEMBL4078429)
Affinity DataKi:  800nMAssay Description:Competitive inhibition of biotinylated ephrin-A1-Fc binding to EphA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50234948(CHEMBL4078429)
Affinity DataIC50:  794nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse EphA2 receptor preincubated for 1 hr followed by biotinylated ephrin-A1-Fc addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
University Of Parma

Curated by ChEMBL
LigandPNGBDBM50234948(CHEMBL4078429)
Affinity DataIC50:  6.40E+3nMAssay Description:Antagonist activity at EphA2-Fc in human PC3 cells assessed as reduction in ephrin-A1-Fc stimulated EphA2 phosphorylation preincubated for 20 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50234948(CHEMBL4078429)
Affinity DataIC50:  800nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse EphA2 receptor preincubated for 1 hr followed by biotinylated ephrin-A1-Fc addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50234948(CHEMBL4078429)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed