BDBM50235350 CHEMBL4094562

SMILES C#Cc1nc(Nc2ccccc2)nc2[nH]cnc12

InChI Key InChIKey=PRKFJWMFXNJCLC-UHFFFAOYSA-N

Data  23 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50235350   

TargetCyclin-A2(Bos taurus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  2.10E+4nMAssay Description:In vitro inhibitory concentration against angiotensin-converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  5.54E+4nMAssay Description:Inhibition of human AKT2 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  4.04E+4nMAssay Description:Inhibition of human CDK1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  150nMAssay Description:Inhibition of human NEK2 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human ChK1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  7.67E+4nMAssay Description:Inhibition of human CDK7 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human Plk1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human P70S6K by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human ChK2 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human Aurora A by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  2.28E+4nMAssay Description:Inhibition of human RSK1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  2.64E+4nMAssay Description:Inhibition of human ERK1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  4.02E+4nMAssay Description:Inhibition of human CK1d by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  1.31E+4nMAssay Description:Inhibition of human ABL by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  2.09E+4nMAssay Description:Inhibition of human FYN by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  2.48E+4nMAssay Description:Inhibition of human LYN by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  8.68E+4nMAssay Description:Inhibition of human MET by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of human LCK by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of human SRC by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of human GSK-3beta by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  2.22E+4nMAssay Description:Inhibition of human ERK2 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235350(CHEMBL4094562)
Affinity DataIC50:  2.08E+4nMAssay Description:Inhibition of human NEK1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed