BDBM50235468 CHEMBL4073585

SMILES Cc1ccc(cc1)-c1cc2c(NC(c3ccc4OCCc4c3)P(O)(O)=O)ncnc2s1

InChI Key InChIKey=ORNKDTLGUAHCGN-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235468   

TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL

LigandBDBM50235468(CHEMBL4073585)Copy SMILESCopy InChI

Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of N-terminal His-tagged human recombinant FPPS expressed in Escherichia coli BL21 (DE3) using GPP and [3H]-IPP as substrate preincubated ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI